Probabilistic genotyping software (PGS) is used in criminal investigations to help link a genetic sample — such as a sample from crime-scene evidence — to a person of interest (POI).
PGS Validation process and Interpretability materials (wip list)
- The Dawning of a New Era in DNA Profiling
- Government Accountability Office Spotlight on PGS
- Establishing the Limits of TrueAllele® Casework: A Validation Study
- Testing likelihood ratios produced from complex DNA profiles
- Validating TrueAllele DNA mixture interpretation
- The interpretation of single source and mixed DNA profiles
- A series of recommended tests when validating probabilistic DNA profile interpretation software
- A comparison of statistical models for the analysis of complex forensic DNA profiles
- DNA commission of the International Society of Forensic Genetics: Recommendations on the evaluation of STR typing results that may include drop-out and/or drop-in using probabilistic methods
- DNA Mixture Interpretation: A NIST Scientific Foundation Review
- Correcting forensic DNA errors
- Genetic Data and Civil Rights
- STRmix™ collaborative exercise on DNA mixture interpretation
- Estimating the number of contributors to a DNA profile using decision trees
- Accurate assessment of the weight of evidence for DNA mixtures by integrating the likelihood ratio
- NIST interlaboratory studies involving DNA mixtures (MIX13): A modern analysis
- Interpol review of forensic biology and forensic DNA typing 2016-2019
- Genotyping and interpretation of STR-DNA: Low-template, mixtures and database matches—Twenty years of research and development
- Validation of a DNA mixture statistics tool incorporating allelic drop-out and drop-in