/t-cell-clf

T cell type classification using CNN

Primary LanguageR

Prediction of T cell type based on TCR beta chain sequences using Convolutional Neural Networks

This repo contains the code and the report of a final project for the course Algorithms for Bioinformatics held at the Technical University of Denmark, Lyngby, by professor Morten Nielsen. The paper produced during the project can also be found in the repo.

Description

T helper and T killer cells are two different type of T cells and are differentiated on their expression of either CD4 or CD8 molecules. In this study, Convolutional Neural Networks (CNNs) are applied to predict the type of T cell based on the beta chain sequence of the T cell receptor (TCR).