cFDAP v.0.1.0

cFDAP is a command-line Linux tool for fitting FRAP/FDAP data.

The overall goal of cFDAP is to provide a fast and robust way to extract kinetic parameters from FRAP/FDAP data gathered from outgrowths of living neuronal cells. Nevetheless, the code can be relatively simply adapted to any experiment outline, which, in turn, requires theoretical expressions for FRAP(t)/FDAP(t) signals be hardcoded explicitly (for more details please read Igaev et al. (2015) Biophys. J. 107: 2567-2578).

New

30.08.2016

A new option "-w" has been introduced which allows the user to choose between weighted and unweighted fitting.
09.02.2016

GSL 2.0 support has been implemented.
13.09.2015

Several bugs have been fixed. From now on, cFDAP and curve/error files must be located in the same folder.
12.08.2015

cFDAP now supports kinetic models with 1 and 2 fit parameters and calculates 95%, 97.5% and 99.9% confidence intervals.

Requirements

To successfully compile cFDAP, you need to install the GNU Scientific Library (http://www.gnu.org/software/gsl/). For Ubuntu/Debian, one needs to install gsl-bin (binary package), libgsl2 (library package) and, optionally, libgsl-dev (development package).

Compilation

cc cFDAP.c -o cFDAP -lgsl -lgslcblas -lm

Usage

To get quick start just run

./cFDAP

Copying

cFDAP is licensed under a GPL license. That means that distributing the code is only allowed under the same terms.

TODO

statically linked GSL 2.0
cFDAP version for Windows 7
a simple GUI (preferably a Fiji plugin)