normalise_data error: Error in solve.default(ac %*% t(ac))

Question

normalise_data error: Error in solve.default(ac %*% t(ac))

Closed this issue 4 years ago · 1 comments

tmmack commented 4 years ago

When I run the normalise_data step I get the following error:

Error in solve.default(ac %*% t(ac)) :
Lapack routine dgesv: system is exactly singular: U[1,1] = 0

Does anyone know what this means or how to fix it?

Thanks!

Answer 1 · 2021-02-24T12:36:58.000Z

Hi,
I think it is related to your data design and your data matrix. Could you please share the details about the matrix design (conditions, batch...) and the replicated samples ?

Best wishes,
Marie