Introduction

This is the software implementing the models used by the Group of Prof. Heiko Rieger at Saarland University to study vascularized tumour growth of tumor multi-cellular spheroids, interstitial fluid flow, drug delivery and oxygenation.

We publish it here to foster good scientific practices, i.e. to facilitate reproduction of our work by interested parties.

For more information see http://www.uni-saarland.de/fak7/rieger/homepage/research/tumor/tumor.html

Building

Requirements

trilinos
tbb
cimg
boost
HDF5-cpp-wrapper (https://github.com/DaWelter/HDF5-cpp-wrapper)
numpycpp (https://github.com/DaWelter/numpycpp)

Successfully built on

4.1.11-gentoo-ARCH
Ubuntu 16.04 4.4.0-45-generic #66-Ubuntu

Build process

CMake is our build system. You most likely need to configure the build according to your system specifics. To do so we recommended to create a shell script with the call to cmake. We have several examples in the install_helpers directory.

Basic CMake usage is as follows

$mkdir build  # create your build directory
$cd build
$cmake -DCMAKE_INSTALL_PREFIX=your_install_dir path_to_tumorcode
$make
$make install

The install command is required since it copies generated python libraries to their proper place within the py subdirectory. Note that you can set CMAKE_INSTALL_PREFIX to your source directory, which is useful for development.

Details

Here is a list of debian packages you will need: sudo apt-get install cmake gfortran libblas-dev liblapack-dev python2.7-dev libboost-dev libboost-python-dev python-numpy python-matplotlib libboost-program-options-dev libpng16-dev libtbb-dev libeigen3-dev python-h5py python-scipy povray mpi-default-dev libmumps-dev libsuperlu-dev libhdf5-openmpi-dev libptscotch-dev binutils-dev libiberty-dev libtrilinos-*

Our HDF5-cpp-wrapper is a lightweight c++ library around HDF5. Get it by git clone https://github.com/DaWelter/HDF5-cpp-wrapper.git As it is only a single-header you can simply put a link to it in a directory in your include paths.

NumpyCPP is our C++ wrapper around the numpy C API. Get it by git clone https://github.com/DaWelter/numpycpp.git. Compile and install by

$cd numpycpp
$mkdir build
$cmake -DCMAKE_INSTALL_PREFIX=your_install_dir_defaulting_to_usr/local_or_something_like_that ../
$make
$make install

Issues

Linking problems with HDF5 and h5py

IMPORTANT: We fetch object references pertaining to the HDF5 library linked with h5py and use functions on them pertaining to the HDF5 lib linked to our code, assuming both libraries are the same. THIS MIGHT, HOWEVER, NOT BE THE CASE.

If so, on Ubuntu 16 for instance, you have to compile h5py by yourself. Here is how you can achieve this:

Install the requirements sudo apt-get install cython python-mpi4py python-pkgconfig. Then get the h5py source, e.g. from GitHub git clone https://github.com/h5py. Then build and install by

$cd h5py
$python2 setup.py configure --hdf5=/usr/include/hdf5/openmpi --mpi
$python2 setup.py build
$sudo python2 setup.py install
# or if you want to install it in a custom directory
$python2 setup.py install --prefix=target_dir

By --hdf5=... and --mpi we request to link against the hdf5 library that is installed by respective debian packages, which happen to be compiled with MPI Support.

MPI

This software performs all computations locally, as opposed to distributed HPC. Therefore MPI is NOT required. However, it should do no harm if trilinos and other packages are linked to MPI.

You might have to link against libmpi_cxx.so or do $export LD_PRELOAD=/usr/lib/libmpi_cxx.so prior to running our code, though.

Compiling Trilinos without MPI

We usually completely eliminate MPI from your build to avoid any potential for trouble. Therefore we compile the Trilinos suite by ourselves. To aid people in doing the same we provide configure scripts located in install_helpers.

newbthenewbd/tumorcode