niu-lab/msisensor2

We have downloaded two version software in November 2019 and 2020 respectively.However,the results of tumor only from these two versions were inconsistent.Is it normal?

biofer opened this issue · 0 comments

The first version: Software downloaded on November 12, 2019
Result

loading bed regions ...
loading homopolymer and microsatellite sites ...
Total loading windows:  61 
Total loading homopolymer and microsatellites:  71 
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*** Summary information ***

Number of total sites: 71
Number of sites with enough coverage: 68
Number of MSI sites: 1
MSI score(%): 1.47059

Total time consumed:  11 secs

The second version: Software downloaded on August 28, 2020
Result

loading bed regions ...
loading homopolymer and microsatellite sites ...
Total loading windows:  61 
Total loading homopolymer and microsatellites:  71 
......
......
......
*** Summary information ***

Number of total sites: 71
Number of sites with enough coverage: 0
Number of MSI sites: 0
MSI score(%): 0

Total time consumed:  3 secs

The results from these two versions were inconsistent. No site was covered from the second version. Is it normal?

additional information:
The pair sample Result

loading bed regions ...
loading homopolymer and microsatellite sites ...
Total loading windows:  285 
Total loading homopolymer and microsatellites:  844 
*** Summary information ***

Number of total sites: 844
Number of sites with enough coverage: 709
Number of MSI sites: 45
MSI score(%): 6.34697

Total time consumed:  188 secs