In order to run PyOT you need:

Python 2.7+ or Pypy 1.7+ (2.2+ are HIGHLY recommended)
Twisted 10+
zope.interface (any version that works with your twisted version, PyOT does't directly depend on this)
MySQLdb 1.2.3+ (or pymysql) (1.2.4+ recommended)
Optional: cjson/usjon/simplejson (gives a speedup to saving and loading of players when your using CPython)
Optional: pywin32 if you intend to use IOCP (default on windows)

Links for Windows:

and last

Base-13.X.YY.win32-py2.7.exe (X = a month and YY = a day, this package gets updated all the time!) http://www.lfd.uci.edu/~gohlke/pythonlibs/#base

note: http://www.lfd.uci.edu/~gohlke/pythonlibs/ (This site also got 64bit editions of all the libs)

Copy "config.py.dist" to "config.py" and edit it to match your database settings.

pacman -S python2 mysql-python twisted python-cjson python-distribute

apt-get install python-twisted python-setuptools python-cjson python-mysqldb python2.7

An alternative method is required on older versions of Ubuntu and Debian, since those versions only have python 2.6 or below as standard support.

The easy way will be to update your debian sources to get Python 2.7, like this:

nano (or vi) /etc/apt/sources.list

add this line in the end of the document:

and save (nano = ctrl + O, followed up by CTRL + X to quit), (vi = ESC :w, followed up by :quit)

apt-get update

apt-get upgrade

Then follow the Debian Wheezy installation instructions above.

You can find additional documentation of PyOT here: http://vapus.net/pyot_doc/index.html