You will need the following properly installed on your computer:
Install yarn (or use NPM if you prefer):
brew install yarn
Install Truffle:
yarn global add truffle
Ensure you have truffle 5. Running truffle version should output look something like:
Truffle v5.0.21 (core: 5.0.21)
Solidity v0.5.0 (solc-js)
Node v10.13.0
Web3.js v1.0.0-beta.37
Install Vyper with a virtualenv
Once your virtualenv is activated, running vyper --version should output:
0.1.0b10
Install project dependencies
$ yarn