/AHI1

3D Modelling of AHI1 Disease

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AHI1

3D Modelling of AHI1 Disease Protein Coding Gene

Protein modelling of disease protein coding gene AHI1 using homology modelling from SWISS-Model. The final model can be viewed and edited with PyMol. Mutations were highlighted and labelled in the model based on type (missense, nonsense, insertion/deletion, etc). Mutations were isolated in the WD40 domain regions of AHI1 and coloured accordingly.

The final AHI1 protein modelling file can be found in AHI1_WD40domain.pse

Screenshots of the 3D Model in Different Views

Stick Model

Captures highlighted mutations in amino acid structure.

Highlighted Barrels

Two different angles capturing highlighted mutations in secondary protein structure, with mutations showing amino acid structure.

Cartoon Model

Captures highlighted mutations on the surface of the protein.