/scMD

Cell type deconvolution of bulk DNA methylation data using single-cell DNA methylation references

Primary LanguageR

scMD

scMD (single cell Methylation Deconvolution), a cellular deconvolution framework to reliably estimate cell type fractions from tissue-level DNAm data with single-cell DNAm references.

Installation

devtools::install_github("randel/scMD")

Workflow

Tutorial

https://randel.github.io/scMD/

Reference

Manqi Cai, Jingtian Zhou, Chris McKennan, Jiebiao Wang. scMD facilitates cell type deconvolution using single-cell DNA methylation references. Communications Biology 2024. https://www.nature.com/articles/s42003-023-05690-5