This is a modular implementation of the Guyton 1992 model, based on the
original (monolithic) Fortran 77 code and a faithful translation of this
code into C++ by Thibault Grosse.
The intention of this project is to develop a significantly more detailed
model of renal function to replace the renal block of the Guyton 1992 model.
This directory contains the following files:
README This file.
Makefile The Makefile to build a binary of the model.
src/ The directory containing the source of the model.
guyton92 The main module of the Guyton 1992 model.
guyton92_step A module for simulating time-steps of the model.
params A module that defines a struct of all model parameters.
read_params A module for reading parameter values from files.
read_vars A module for reading state variable values from files.
read_exp A module for processing model experiments.
debug Support for debugging and instrumentation of the model.
utils Utility functions for performing calculations.
sensitivity A sensitivity analyser for individual modules.
params.sh A script to build the params module.
params.lst The list of all model parameters.
params.val The list of default parameter values.
vars.sh A script to build vars module.
vars.lst The list of all model state variables.
vars.val The list of default state variable values.
module_renal The renal portion of the model, in a separate module.
module_circdyn The circulatory dynamics portion of the model.
module_autonom The autonomic circulation control module.
module_aldost The aldosterone module.
module_angio The angiotensin module.
module_anp The atrial natriuretic peptide (ANP) module.
module_rbc The red blood cell (RBC) and viscosity module.
module_o2deliv The O2 delivery and blood flow autoregulation module.
module_volrec The volume receptors module.
module_adh The antidiuretic hormone (ADH) module.
module_stress The stress relaxation module.
module_thirst The thirst drive module.
module_baro The baroreceptor adaptation module.
module_special The special circulatory variables module.
module_capdyn The capillary dynamics module.
module_puldyn The pulmonary fluid dynamics module.
module_electro The electrolytes module.
module_kidney The replacement for the original renal module.
model_moore94 The Moore 1994 model of renal autoregulation.
exp_rapidreg An experiment in rapid autoregulation.
exp_transfuse An experiment in transfusion and blood loss.
filter_times A filter to reduce the number of state notifications.
instr_pa A simple instrument that displays arterial pressure.
instr_renal An instrument that displays the renal module outputs.
instr_vars An instrument to display arbitrary model outputs.
Doxyfile The configuration file for source code documentation.
mainpage.h The main page of the Doxygen documentation.
build/ The directory containing the compiled binary.
guyton92 The binary of the model.
doc/ The directory containing the source code documentation.
index.html The main page of the documentation.
exps/ The directory containing model experiments.
utils/ The directory for utilities related to the model.
find_vars.sh A script to find parameter and variable references.
sens_plots.sh A script to produce plots of module output sensitivity.
The following targets are defined in the Makefile:
all: Build the model binary and documentation (default target).
model: Build the model binary.
docs: Generate documentation of the model source code (using doxygen).
clean: Remove temporary files.
clobber: Remove the model binary in addition to temporary files.