- Estimates the proportion of genome shared IBD between pairs of isolates
- Detects genomic regions that are identical by descent (IBD) between pairs of isolates
- Allows IBD detection in isolates with multiple infections
- Identifies genomic loci under positive selection
- Creates networks of related isolates
- Includes multiple graphical functions to explore the results
isoRelate is currently available to install as a development version from Github:
# first install the devtools package
install.packages("devtools")
# install isoRelate using devtools packages
devtools::install_github("bahlolab/isoRelate")
See the introduction vignette for details.
Henden L, Lee S, Mueller I, Barry A, Bahlo M. 2016. Detecting selection signals in Plasmodium falciparum using identity-by-descent analysis. bioRxiv. doi: http://dx.doi.org/10.1101/088039