In this repository you will find R code for the 101 DNA methylation data processing and normalization pipelines described in Ori et al., 2021. See the "function_runPipelines.R" script in the "pipeline" directory for an R function that contains code for all the 101 pipelines. The code also contains an R function that will allow you to easily run multiple analytical pipelines in a systematic manner.
In the "biomarker" directory you can also find R scripts to get estimates for DNAm predictors that are described in the manuscript. I could not make code for all predictors available because of proprietary licences for the GrimAge predictors and its associated plasma protein predictors. The Horvath DNAm clock can be run using the online calculator (http://dnamage.genetics.ucla.edu/).