Multi-cell population modelling predicts metabolic activity of midbrain organoids
Model building was done with scFASTCORMICS, see: scFASTCORMICS
Paper: Miro1 mutation leads to metabolic maladaptation resulting in Parkinson’s disease-associated dopaminergic neuron loss
Alise Zagare1*, Thomas Sauter2*, Kyriaki Barmpa1, Maria Pacheco2, Rejko Krüger3,4, Jens Christian Schwamborn1*#, Claudia Saraiva1#
Affiliations
- Developmental and Cellular Biology, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 2, place de l’Université, L-4365 Esch-sur-Alzette, Luxembourg.
- Systems Biology group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 2, place de l’Université, L-4365 Esch-sur-Alzette, Luxembourg.
- Translational Neuroscience, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 2, place de l’Université, L-4365 Esch-sur-Alzette, Luxembourg.
- Transversal Translational Medicine, Luxembourg Institute of Health (LIH), 1 A-B rue Thomas Edison, L-1445 Strassen, Luxembourg
*Equal contribution