/MMRNHep

Code used in publication Clasen et al to run flux simulations and generate Figures

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MMRNHep Clasen et al (in preperation)

Data and scripts for Clasen et al. Please see publication for detail.

All models are available in the model directory. This includes the mouse model MMRN, the generic mouse hepatic model MMRNHep, as well as all constrained models

Scripts available are as follows:

1_MAIN.R : R script for the analysis of transcriptomics data
2_Eflux.ipynb : Jupyter notebook to generate constraints
3_MAIN.m : MATLAB script to perform flux simulations