/Malezieux_CellRep_2020

analysis codes for Malezieux, Kees, and Mulle (2020). Cell Reports

Primary LanguagePythonGNU General Public License v3.0GPL-3.0

Malezieux_CellRep_2020

Analysis codes for Malezieux, Kees, and Mulle (2020). Cell Reports

Raw data files (.abf) from the primary population of cells were processed using the following scripts:

  • Malezieux_CellRep_load_data.py

    performs brain state classification, downsamples and smooths membrane potential and LFP traces

  • Malezieux_CellRep_load_data_CS.py

    detects spikes, spikelets, and complex spikes

  • Malezieux_CellRep_load_data_hf.py

    analyzes theta coherence between membrane potential and LFP traces

Next, these datasets were combined and further processed using the following script:

  • Malezieux_CellRep_combine_datasets.py

The python dictionaries that result from the above script can be found for public download at [https://datadryad.org/stash/dataset/doi:10.5061/dryad.jq2bvq86r]

Other raw data files (.abf) from a separate population of cells subjected to the Rin protocol were processed using the following script:

  • Malezieux_CellRep_load_data_Rin.py

The python dictionaries that result from the above script can be found for public download at http://datadryad.org/stash/dataset/doi:10.5061/dryad.jq2bvq86r

The remaining scripts can be run on these python dictionaries to create the main data figures and compute the statistics found in the paper.

Note: the .yaml file is provided to facilitate the duplication of the Python environment used to write the code

Metadata is found in the .xlxs file

  • sheet 'Recorded cells' has the list of cells in the main dataset and their properties (see Tables S1 and S2 from the paper)

  • sheet 'Dataset keys' is a list and explanation of the keys of the dictionaries provided for each cell in the main dataset

  • sheet 'Dataset_Rin keys' is a list and explanation of the keys of the dictionaries provided for each cell in the input resistance dataset