Repository dedicated to harbour all the scripts used to analyse the data product of our Placenta Infection experiments.
The single-cell RNA-seq data from infected placenta can be browsed and visualised in the Reproductive Cell Atlas.
This repository has the following sections of codes:
Explants_scRNAseq: single-cell RNAseq analysis of placental explants compared to fresh tissue.Explants_cellHashing_scRNAseq: single-cell RNAseq analysis of independent placental regions processed using cell hashing.PlacentaInfection_scRNAseq: single-cell RNAseq analysis of infected placental explants.PlacentaInfection_snRNAseq: single-nuclei RNAseq analysis of placental explants infected with Plasmodium falciparum.Plasmodium_falciparum_scRNAseq: single-cell RNAseq analysis of Plasmodium falciparum parasites.
Citation:
Acute response to pathogens in the early human placenta at single cell resolution
Regina Hoo*, Elias R. Ruiz-Morales*, Iva Kelava*, Mukul Rawat, Cecilia Icoresi Mazzeo, Elizabeth Tuck, Carmen Sancho-Serra, Sara Chelaghma, Alexander V. Predeus, Simon Murray, David Fernandez-Antoran, Ross F. Waller, Damiana Álvarez-Errico, Marcus C. S. Lee#, Roser Vento-Tormo#
*co-first #Co-corresponding