/merip_reanalysis_scripts

Scripts for paper entitled "Limits in the detection of m6A changes using MeRIP/m6A-seq

Primary LanguageR

Scripts for paper on MeRIP-seq reproducibility and detection of changes in m6A

BioRxiv preprint here.

This repository is for scripts to generate the figures. Bam files are too large to host here, but it is possible to download the fastqs from GEO/SRA and rerun alignment using STAR. Alternatively, run_full_analysis.sh provides a wrapper script to generate plots from saved results (requires all R packages and gtf files for mouse and human).

Please see R package DEQ to run DESeq2, edgeR, and QNB from input and IP bam files as described in our paper.