/Hamburg_MRF_workshop_VUMC_results

Results using the Vanderbilt MR fingerprinting patch acquired at the Philips Research MRF workshop held in Hamburg in August 2017.

Primary LanguageJupyter NotebookMIT LicenseMIT

Contents

  1. How do I get set up to run code locally?
  2. Scan Descriptions
  3. Notes
  4. Maps
  5. Plots
  6. ROI Measurements

How to set up to run code locally

Scan Descriptions

Scan Name Scan Time mm:ss TI ms TR ms TE ms Max Flip Angle Repetition Delay ms TFE Inversion Delay ms TFE Shot Interval ms Dynamics Spiral Duration ms Spiral Interleaves Reconstructed
VUMC_MRF_1000_TE3.3_FSC 10:14.0 20 16 3.3 70 N/A 8012.00 26000 24 6.7578 24 YES
VUMC_MRF_1000_TE3.3_US 00:16.0 20 16 3.3 70 N/A 8012.00 26000 1 6.7578 24 YES
VUMC_MRF_1000_TE5.0_FSC 10:14.0 20 16 5.0 70 N/A 8012.00 26000 24 6.7578 24 YES
VUMC_MRF_1000_TE5.0_US 00:16.0 20 16 5.0 70 N/A 8012.00 26000 1 6.7578 24 YES
VUMC_MRF_210_TE3.3_FSC 03:04.8 28 28 3.3 70 1000 2953.96 6880 27 6.8843 27 YES
VUMC_MRF_210_TE3.3_US 00:26.6 28 28 3.3 70 1000 2953.96 6880 4 6.8288 24 YES
VUMC_MRF_210_TE4.0_FSC 03:04.8 28 28 4.0 70 1000 2953.96 6880 27 6.8843 27 YES
VUMC_MRF_210_TE4.0_US 00:26.6 28 28 4.0 70 1000 2953.96 6880 4 6.8288 24 YES
VUMC_MRF_500_TE3.3_FSC 07:01.5 15 15 3.3 60 N/A 3757.49 18000 24 5.8876 24 YES
VUMC_MRF_500_TE3.3_US 00:07.5 15 15 3.3 60 N/A 3757.49 18000 1 5.8876 24 YES
VUMC_MRF_500_TE5.2_FSC 07:01.5 15 15 5.2 60 N/A 3757.49 18000 24 5.8876 24 YES
VUMC_MRF_500_TE5.2_US 00:07.5 15 15 5.2 60 N/A 3757.49 18000 1 5.8876 24 YES

Notes

  • US stands for "undersampled", i.e., a single spiral interleaf per readout of the fingerprint pattern.
  • FSC stands for "fully sampled center", i.e., 24 spiral interleaves avaialble per readout of the fingerprint pattern.
  • Spirals are variable density with the change to x2 additional undersampling (24 to 48 interleaves) at 60% from k-space center.
  • Dynamics are used for two purposes in the above scans.
    1. Repeated dynamics achieved the short relaxation time interval feature (length 210 pattern) by using the first 3 dynamics as the "dummy" repetitions.
    2. Repeated dynamics collected additional interleaves to fully sample the spiral trajectory.
  • Spirals are rotated by the Golden Angle, which is 180 * (3 - sqrt(5)) = 137.50776405 degrees (full projection radial MRI golden angle is 111.246117975 degrees)
  • FSC 210 scans had an incorrect setting of 27 spiral interleaves and therefore have a mismatch between acquired and trajectory-measured spiral. Reconstructions were performed by synthesizing the trajectory from the gradient waveform values along with eddy current constants and gradient delay time estimated from the measured spiral trajectory for the undersampled 210 scans. The method of calibration was a slightly tweaked version of the approach described in this paper.
  • Excitation RF was selected to have a higher time-bandwidth product (RFex rf_shape = sg_500_200_0).
  • No off-resonance correction is applied in current reconstructions. A single delta B0 fieldmap was acquired at the end of the scan session and appears to not agree with most scans. Center frequency was selected once at the beginning of the scan session with "selective F0" and likely drifted over the long scan session duration.
  • Alternating RF phase in length 1000 pattern is removed during corrections applied to raw k-space data and the alternating phase is added back into the even numbered complex images before matching to the dictionary.
  • ROI measurements use a circular shape with radius of 7 pixels yielding 149 samples in each ROI.
  • Concordance Correlation Coefficient values are reported on the plots showing measured versus true T1 and T2 values.

Maps

Full size map images visible at this link: Maps VUMC_MRF_1000_TE3.3_FSC VUMC_MRF_1000_TE3.3_US VUMC_MRF_1000_TE5.0_FSC VUMC_MRF_1000_TE5.0_US VUMC_MRF_210_TE3.3_FSC VUMC_MRF_210_TE3.3_US VUMC_MRF_210_TE4.0_FSC VUMC_MRF_210_TE4.0_US VUMC_MRF_500_TE3.3_FSC VUMC_MRF_500_TE3.3_US VUMC_MRF_500_TE5.2_FSC VUMC_MRF_500_TE5.2_US

Plots

Full size plot images visible at this link: Plots VUMC_MRF_1000_TE3.3_FSC VUMC_MRF_1000_TE3.3_US VUMC_MRF_1000_TE5.0_FSC VUMC_MRF_1000_TE5.0_US VUMC_MRF_210_TE3.3_FSC VUMC_MRF_210_TE3.3_US VUMC_MRF_210_TE4.0_FSC VUMC_MRF_210_TE4.0_US VUMC_MRF_500_TE3.3_FSC VUMC_MRF_500_TE3.3_US VUMC_MRF_500_TE5.2_FSC VUMC_MRF_500_TE5.2_US

ROI Measurements

T1 mean

source_name ROI_01 ROI_02 ROI_03 ROI_04 ROI_05 ROI_06 ROI_07 ROI_08 ROI_09 ROI_10 ROI_11 ROI_12 ROI_13 ROI_14
TRUTH 2480.0000 2173.0000 1907.0000 1604.0000 1332.0000 1044.0000 801.7000 608.6000 458.4000 336.5000 244.2000 176.6000 126.9000 90.9000
VUMC_MRF_1000_TE3.3_FSC 2620.9396 2329.6644 2152.3490 1849.7987 1503.7584 1219.3289 988.3893 776.3758 547.1141 396.3758 272.4161 173.4228 147.3826 126.0403
VUMC_MRF_1000_TE3.3_US 2642.9530 2372.0805 2157.9866 1891.5436 1514.4966 1214.8993 993.2215 786.0403 572.4832 404.0268 272.5503 172.2819 145.8389 123.9597
VUMC_MRF_1000_TE5.0_FSC 2650.7383 2380.1342 2166.8456 1883.3557 1526.1745 1305.7718 1041.0738 824.7651 559.7987 404.1611 295.5034 204.0940 175.0336 188.6577
VUMC_MRF_1000_TE5.0_US 2661.2081 2405.1007 2160.9396 1885.3691 1512.4832 1269.9329 1011.6107 789.7315 554.1611 393.4228 288.0537 200.4698 167.5839 165.0738
VUMC_MRF_210_TE3.3_FSC 2714.6309 2212.3490 2086.7114 1828.3221 1423.3557 1187.9195 842.5503 616.7785 444.2953 326.3758 258.3221 176.6443 147.0470 116.5101
VUMC_MRF_210_TE3.3_US 2657.9866 2339.5973 2172.2148 1912.8859 1513.0201 1126.0403 867.2483 640.4698 473.5570 352.4161 249.7315 164.2953 145.7047 103.1409
VUMC_MRF_210_TE4.0_FSC 2638.6577 2132.7517 2043.6242 1745.6376 1388.5906 1153.0201 824.0268 616.9128 447.1812 328.9933 257.8523 177.8523 147.9195 117.3826
VUMC_MRF_210_TE4.0_US 2623.6242 2321.0738 2152.8859 1853.6913 1452.3490 1080.9396 844.4966 641.5436 476.5772 357.1812 249.5973 162.4832 149.1946 102.6846
VUMC_MRF_500_TE3.3_FSC 2664.4295 2330.2013 2071.5436 1715.7047 1295.0336 1022.0134 780.0000 574.4295 429.2617 328.1208 232.4161 155.0336 133.4899 114.0268
VUMC_MRF_500_TE3.3_US 2693.4228 2290.4698 2057.5839 1706.9799 1326.0403 1006.0403 773.2886 574.1611 433.0872 338.1879 236.3087 156.9128 136.7785 115.0336
VUMC_MRF_500_TE5.2_FSC 2666.5772 2397.8523 2119.1946 1905.3691 1500.8054 1104.2953 824.0268 639.9329 512.8859 383.8255 267.3154 174.6980 161.3423 113.6913
VUMC_MRF_500_TE5.2_US 2672.7517 2364.0268 2105.6376 1876.3758 1479.3289 1059.0604 799.1946 620.4698 497.9195 383.5570 263.0872 169.5302 156.1074 108.8188

T2 mean

source_name ROI_01 ROI_02 ROI_03 ROI_04 ROI_05 ROI_06 ROI_07 ROI_08 ROI_09 ROI_10 ROI_11 ROI_12 ROI_13 ROI_14
TRUTH 581.3000 403.5000 278.1000 190.9400 133.2700 96.8900 64.0700 46.4200 31.9700 22.5600 15.8130 11.2370 7.9110 5.5920
VUMC_MRF_1000_TE3.3_FSC 477.5839 288.7248 218.9262 179.7181 151.2752 124.9664 95.4228 70.9530 53.3154 48.6577 31.5570 24.6711 28.2953 34.1879
VUMC_MRF_1000_TE3.3_US 498.7248 301.4094 217.8792 186.1342 165.6107 123.7718 97.2081 71.6510 55.9463 50.7651 29.6644 22.4966 25.4094 30.6711
VUMC_MRF_1000_TE5.0_FSC 419.2617 244.0268 177.0201 162.3490 162.1074 163.6107 112.0403 74.4295 51.1007 49.8121 36.3490 32.0671 37.5302 60.3087
VUMC_MRF_1000_TE5.0_US 400.0000 231.6779 168.3758 155.0336 154.8591 151.8389 103.4362 69.4765 49.1544 45.4765 32.1477 28.2282 32.0268 49.2215
VUMC_MRF_210_TE3.3_FSC 625.7718 352.4161 233.4899 176.4027 159.4765 111.5839 79.6510 39.5034 24.0403 19.5436 3.3557 2.7517 6.7517 5.2886
VUMC_MRF_210_TE3.3_US 618.9262 352.0805 260.8054 176.1342 134.1074 107.1544 72.0000 47.7852 34.8322 32.1477 7.0201 3.8523 15.8255 8.5772
VUMC_MRF_210_TE4.0_FSC 570.2013 313.1544 220.4027 158.5101 138.6309 113.6510 68.3893 37.9463 23.3960 20.3893 2.6309 2.9799 6.4430 4.0537
VUMC_MRF_210_TE4.0_US 614.1611 347.3826 265.7047 177.7584 132.7919 109.6242 70.0268 50.0805 37.1275 34.0671 10.8322 7.4899 22.2819 8.3356
VUMC_MRF_500_TE3.3_FSC 577.7181 329.9329 225.5705 175.0336 136.4295 94.2550 67.7450 42.9396 30.3356 23.2886 4.2013 2.3490 2.7651 2.0000
VUMC_MRF_500_TE3.3_US 562.8859 290.2685 208.3624 154.3758 120.4698 80.8054 58.3758 37.0336 26.0671 22.7383 3.0336 2.0671 2.3490 2.0403
VUMC_MRF_500_TE5.2_FSC 591.4094 369.8658 240.4027 193.1544 154.9396 102.5369 67.2886 47.6644 41.6779 35.7315 17.8658 13.1409 20.4698 10.1745
VUMC_MRF_500_TE5.2_US 590.7383 341.6107 233.1141 174.5369 140.8725 95.8658 62.3356 43.7584 36.6711 33.0470 14.5235 9.5973 15.3826 4.8456

T1 sigma

source_name ROI_01 ROI_02 ROI_03 ROI_04 ROI_05 ROI_06 ROI_07 ROI_08 ROI_09 ROI_10 ROI_11 ROI_12 ROI_13 ROI_14
TRUTH 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000
VUMC_MRF_1000_TE3.3_FSC 23.0552 35.9131 78.4856 89.0678 69.9177 31.2285 52.2089 73.5969 50.2870 38.9423 10.4397 9.6403 8.4146 11.9016
VUMC_MRF_1000_TE3.3_US 39.2067 55.5473 91.1709 94.7880 90.1608 54.0847 58.4631 92.1575 73.1336 51.3325 15.3849 11.3376 7.7198 12.0707
VUMC_MRF_1000_TE5.0_FSC 32.7582 67.9625 136.7731 156.2639 77.9084 77.6790 132.5434 154.8913 102.2944 53.6518 32.3084 25.0409 24.1791 113.2306
VUMC_MRF_1000_TE5.0_US 39.3342 87.7698 162.3366 171.3008 92.9538 99.3118 132.2726 152.0844 109.1620 56.6016 38.3032 34.6281 25.0311 91.8964
VUMC_MRF_210_TE3.3_FSC 135.6193 108.8167 104.5353 173.1442 186.2489 215.2443 111.2227 39.7334 22.7280 14.4827 4.2558 6.3257 9.8984 8.9990
VUMC_MRF_210_TE3.3_US 200.1316 109.5068 135.7404 107.1769 89.0468 90.2760 69.7569 20.3462 13.5604 15.7536 11.5048 10.4787 12.1508 8.1812
VUMC_MRF_210_TE4.0_FSC 112.0247 76.4133 90.1966 167.4947 185.0968 205.8427 86.4223 31.4277 20.9272 15.2344 4.4363 6.5310 11.8136 8.5737
VUMC_MRF_210_TE4.0_US 135.6477 96.0795 102.8795 85.5218 83.6853 68.6486 38.3165 17.6193 13.5453 13.6600 11.1428 9.9936 15.4446 7.2588
VUMC_MRF_500_TE3.3_FSC 27.3956 68.5217 112.6147 137.9691 81.4366 32.3616 21.4350 36.3984 32.6342 18.5767 5.1532 5.1497 6.0321 4.9209
VUMC_MRF_500_TE3.3_US 43.5234 85.9159 104.9044 137.5053 71.6864 44.0948 24.9172 42.2365 36.5746 19.7297 7.4751 5.8007 6.5004 5.1497
VUMC_MRF_500_TE5.2_FSC 26.9577 111.6738 168.9535 199.0739 157.1517 47.5090 54.7095 91.7141 84.1836 46.7830 27.5492 18.6923 28.1564 8.9555
VUMC_MRF_500_TE5.2_US 38.9188 93.7789 184.3628 212.1582 157.5388 39.8535 59.3947 92.4906 84.0951 43.8837 32.5887 19.4289 25.4344 9.6002

T2 sigma

source_name ROI_01 ROI_02 ROI_03 ROI_04 ROI_05 ROI_06 ROI_07 ROI_08 ROI_09 ROI_10 ROI_11 ROI_12 ROI_13 ROI_14
TRUTH 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000
VUMC_MRF_1000_TE3.3_FSC 14.3626 16.9374 17.8636 21.7418 16.8863 7.1494 11.6603 10.8368 8.8157 8.5280 3.3194 4.5477 4.4744 7.6382
VUMC_MRF_1000_TE3.3_US 21.9732 18.5276 20.6165 19.7206 21.8603 14.4569 12.1518 11.4390 11.9706 11.1733 4.8791 5.3822 5.1753 8.1460
VUMC_MRF_1000_TE5.0_FSC 19.1401 15.5059 19.4500 23.0999 19.6672 24.3351 27.4270 21.2940 15.6472 13.5074 10.9858 10.0658 10.9060 48.9753
VUMC_MRF_1000_TE5.0_US 24.7692 19.1510 22.9763 24.7448 23.6988 27.2927 25.4474 21.0307 16.6135 13.3181 12.4382 12.9688 12.2386 42.3644
VUMC_MRF_210_TE3.3_FSC 101.1634 44.6707 24.5480 34.1966 59.9082 44.1883 35.4185 9.7285 12.5558 12.4186 2.3397 0.9719 11.8401 8.1707
VUMC_MRF_210_TE3.3_US 84.6147 32.5758 17.1053 16.0264 19.1435 15.4661 21.4665 4.2116 4.7254 8.3151 6.8915 4.0543 11.3469 10.6550
VUMC_MRF_210_TE4.0_FSC 75.8953 24.3313 23.5062 36.9764 55.8942 44.1635 24.5177 7.8773 10.8919 12.3719 1.9184 1.0032 11.8933 5.7608
VUMC_MRF_210_TE4.0_US 66.9520 22.3726 27.8571 18.8893 20.7323 11.7895 8.0101 3.4081 3.7150 6.0957 8.3572 7.5414 14.3791 9.8101
VUMC_MRF_500_TE3.3_FSC 30.2718 20.1513 16.1656 15.8329 12.3213 5.3184 4.3265 5.0967 5.6444 4.6503 3.6447 1.3898 2.2613 0.0000
VUMC_MRF_500_TE3.3_US 40.0725 26.4561 16.5383 15.6090 11.3528 5.5843 4.1353 5.5973 6.9881 5.1378 2.7273 0.8192 1.7357 0.4915
VUMC_MRF_500_TE5.2_FSC 20.0344 24.8777 33.5084 35.8715 26.1880 9.4658 6.0228 12.7288 14.5715 10.4485 8.8430 10.1934 14.5349 7.7701
VUMC_MRF_500_TE5.2_US 29.5483 26.3569 34.4308 34.8849 25.0333 9.4459 6.0333 12.5825 14.8699 9.9338 10.0065 9.4525 13.0258 6.4690