/CueFearConditioning

MATLAB code for auditory cue-dependent fear conditioning

Primary LanguageMATLABMIT LicenseMIT

CueFearConditioning

MATLAB code for auditory cue-dependent fear conditioning with any aversive stimuli. By default, this code gives 7500 and 2500 Hz pure tones and only 7500 Hz tones are associated with aversive stimuli like footshock. Information of a practical footshock circuit is available here (https://figshare.com/articles/FootshockCircuit/5421613).

Getting Started

Prerequisites

The code has been tested with a USB-6008, MATLAB ver 8.6 (R2015b), and Data Acquisition Toolbox ver 3.5.2 (R2015b).

Installing

  • Install MATLAB, Data Acquisition Toolbox, and Driver (NI-DAQmx).
  • Connect your Ni Daq to your PC.
  • Give your MATLAB path to the m files.

How to use

Run each cell one-by-one.

  • Day 1: habituation

Cell 1.

  • Day 2: conditioning

Cell 2.

  • Day 3, 4: test

Cell 3, 4

DOI

DOI

Versioning

We use SemVer for versioning.

Releases

  • Ver 1.0.0, 2017/09/20: The first release.
  • Pre-release, 2017/09/19

Authors

License

This project is licensed under the MIT License.

Acknowledgments

  • Rodrigo Alejandro Sierra, PhD
  • Lizeth Pedraza, PhD

References

  • Bundel DD, Zussy C, Espallergues J, Gerfen CR, Girault JA, Valjent E (2016) Dopamine D2 receptors gate generalization of conditioned threat responses through mTORC1 signaling in the extended amygdala. Mol Psychiatry 21:1545-1553.