TwitchAdSolutions

This repo aims to provide multiple solutions for blocking Twitch ads.
Don't combine Twitch specific ad blockers.

Recommendation

My recommendation as it seems to be the best and most reliable ad-blocker.

Video Ad-Block, for Twitch (VAFT) - ublock / userscript / ublock (permalink)
- Video Ad-Block, for Twitch fork as a script.
- Message displayed during ads when they are getting blocked.

For the sake of security it's recommended to use a permalink when using uBlock Origin (permalinks do not auto update).

Navigate to the uBlock Origin Dashboard (the extension options)
Under the My filters tab add twitch.tv##+js(twitch-videoad).
Under the Settings tab, enable I am an advanced user, then click the cog that appears. Modify the value of userResourcesLocation from unset to the full url of the solution you wish to use (if a url is already in use, add a space after the existing url). e.g. userResourcesLocation https://github.com/yungsamd17/TwitchAdSolutions/raw/master/vaft/vaft-ublock-origin.js
To ensure uBlock Origin loads the script I recommend that you disable/enable the uBlock Origin extension (or restart your browser).

To stop using a script remove the filter and make the url unset.