/motifValidateAntibody

Pipeline for motif enrichment used in antibody validation

Primary LanguagePython

Commandline Workflow

Software dependency

python bedtool rtool

Reformat Peak file

  • center 100bp window for each peak
  • sort the peak based on the score and compute the peak rank

Motif Overlap

  • given reference genome, overlap pouya motif instance with the peak file

Compute Global Enrichment score

  • run Enricher.sh (developped by Pouya )

Compute Positional and Peak-Rank Enrichment score

  • run computeCentdistScore.py

Compute Avg-combine Score

  • run

Compute Accept and Reject Probability

  • run