Experimental R bindings to the native GenomicsDB library. Only queries are supported for now. For ingestion, use GenomicsDB native command line tool vcf2genomicsdb or gatk GenomicsDBImport.
See GenomicsDB build/install for a docker or a scripted install of GenomicsDB for MacOS and Linux based systems. Use the installed GenomicsDB path as input to GenomicsDB-R configuration. See <path_to_genomicsdb> below.
From R/RStudio
library(remotes)
remotes::install_github("GenomicsDB/GenomicsDB-R", ref="<github_branch>", configure.args="--with-genomicsdb=<path_to_genomicsdb>")