JinmiaoChenLab/GraphST

Question for integrating different sources of ST and scRNA-seq data

Opened this issue · 2 comments

Fanyu000 commented

Hi,
I have used ST data from a study, but because of the lack of corresponding scRNA-seq, I have to use my previous scRNA-seq integrated datasets for reference.

By using this method, I get a set of single cell data distribution in ST tissue visualization figures. Do you think this figure can simulate the authentic cell types distribution in tissue?

Thanks :)

longyahui commented

Hi,

Thank you for your question.

GraphST can accurately project scRNA-seq data into ST sample if both data is matched well enough. I am not sure whether the scRNA-seq and ST data you used are matched. Thanks again.

Best regards,
Yahui
Fanyu000 commented