Merck Sharp & Dohme Corp. a subsidiary of Merck & Co., Inc.
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Pinned Repositories
BioPhi
BioPhi is an open-source antibody design platform. It features methods for automated antibody humanization (Sapiens), humanness evaluation (OASis) and an interface for computer-assisted antibody sequence design.
deepbgc
BGC Detection and Classification Using Deep Learning
DeepNeuralNet-QSAR
Halyard
Halyard is an extremely horizontally scalable Triplestore with support for Named Graphs, designed for integration of extremely large Semantic Data Models, and for storage and SPARQL 1.1 querying of the whole Linked Data universe snapshots.
Line-of-Therapy-Algorithm
This is the Line of Therapy Algorithm, as described in the paper "Temporal phenotyping by mining healthcare data to derive lines of therapy for cancer" pending submission in the Journal of Biomedical Informatics.
matcher
Matcher is a tool for understanding how chemical structure optimization problems have been solved. Matcher enables deep control over searching structure/activity relationships (SAR) derived from large datasets, and takes the form of an accessible web application with simple deployment. Matcher is built around the mmpdb platform.
pkglite
Compact Package Representations
r2rtf
Easily Create Production-Ready Rich Text Format (RTF) Table and Figure
rdf2x
RDF2X converts big RDF datasets to the relational database model, CSV, JSON and ElasticSearch.
Sapiens
Sapiens is a human antibody language model based on BERT.
Merck Sharp & Dohme Corp. a subsidiary of Merck & Co., Inc.'s Repositories
Merck/BioPhi
BioPhi is an open-source antibody design platform. It features methods for automated antibody humanization (Sapiens), humanness evaluation (OASis) and an interface for computer-assisted antibody sequence design.
Merck/r2rtf
Easily Create Production-Ready Rich Text Format (RTF) Table and Figure
Merck/matcher
Matcher is a tool for understanding how chemical structure optimization problems have been solved. Matcher enables deep control over searching structure/activity relationships (SAR) derived from large datasets, and takes the form of an accessible web application with simple deployment. Matcher is built around the mmpdb platform.
Merck/rdf2x
RDF2X converts big RDF datasets to the relational database model, CSV, JSON and ElasticSearch.
Merck/pkglite
Compact Package Representations
Merck/Line-of-Therapy-Algorithm
This is the Line of Therapy Algorithm, as described in the paper "Temporal phenotyping by mining healthcare data to derive lines of therapy for cancer" pending submission in the Journal of Biomedical Informatics.
Merck/sonar-r-plugin
Adds support for R language into SonarQube. It uses output from lintr tool which is processed by the plugin and uploaded into SonarQube server.
Merck/gsDesign2
Group Sequential Design Under Non-Proportional Hazards
Merck/AlgebraicAgents.jl
A lightweight framework to enable hierarchical, heterogeneous dynamical systems co-integration. Batteries included!
Merck/simtrial
Clinical trial simulation for time-to-event endpoints
Merck/metalite.ae
An R package for standard adverse events analysis
Merck/ReactiveDynamics.jl
A Julia package that implements a category of reaction (transportation) network-type dynamical systems.
Merck/metalite
An R package to create metadata structure for ADaM data analysis and reporting
Merck/forestly
Interactive forest plot for adverse events analysis
Merck/boxly
Interactive box plot for clinical trial analysis
Merck/mRNAid
Merck/MolPROP
fuses molecular language and graph representation for property prediction
Merck/bgc-pipeline
Merck/gMCPLite
Lightweight graph-based multiple comparison procedures
Merck/AbLEF
Antibody Langauge Ensemble Fusion - fuses antibody structural ensemble and language representation for property prediction
Merck/psm3mkv
psm3mkv: A package to evaluate the fit and efficiency of three state oncology cost-effectiveness model structures
Merck/CEEDesigns.jl
A decision-making framework for the cost-efficient design of experiments, balancing the value of acquired experimental evidence and incurred costs.
Merck/AbPROP
Merck/simvaxpmx
Elucidating vaccine efficacy using a correlate of protection, demographics, and logistic regression
Merck/ProbeDesign
Merck/wpgsd
Weighted parametric group sequential design
Merck/metalite.sl
An R package designed for the analysis & reporting of subject baseline characteristics in clinical trials.
Merck/puqsar
Merck/.github
Merck/AnNoBrainer