running Pyclone-VI with total copy number

Question

running Pyclone-VI with total copy number

Opened this issue 3 years ago · 2 comments

Hi, I only have total copy number information (and not major and minor cn). I was wondering if it is possible to run Pyclone VI with this limited info. In your earlier versions one could set --prior total_copy_number but I think that parameter is not in the new version? pls advise.

Answer 1 · 2021-10-26T17:42:34.000Z

If you set major_cn to the total copy number and minor_cn to 0 you will achieve something very close to the old total_copy_number flag.

Answer 2 · 2021-10-27T03:20:42.000Z

Thank you

If you set major_cn to the total copy number and minor_cn to 0 you will achieve something very close to the old total_copy_number flag.