DNA damages from various context are mapped onto G4 stuctures with varied stability. The damage propensity is plotted and discussed in detail in the publication.
Change the variables as follow:
- UV damage plots
dmg.names = c('CPD', 'PP')
dmg.type = "UV"
dmg.pattern = c("CT", "TC", "TT")
strand.sensitive = T
combine.plot = F - cisplatin damage
dmg.names = "cisplatin"
dmg.type = "cisplatin"
dmg.pattern = "GG"
strand.sensitive = T - 8oxoG damage
dmg.names = "oxoG"
dmg.type = "oxoG"
dmg.pattern = "G"
strand.sensitive = T - breakage damage
dmg.names = c("sonication", "enzymatic", "ancient")
dmg.type = "breakage"
dmg.pattern = "NN"
strand.sensitive = F
combine.plot = T