An SGC Open Chemistry Networks Project (number 10) dedicated to finding hits vs CHIKV based on a hit containing an naphthoquinone.
You contribute synthetic chemistry and in return the SGC offers biology. Together we can generate tool compounds to understand biology and validate drug targets to help cure disease. Everything is open, with all content governed by a CC-BY-4.0 licence.
If this sounds interesting, and you agree to the simple RULES, you can get started.
For the science background, head to the wiki or check out the living paper that is being written here.
Note that the current status of this project is closed/paused, because cytoxicity is tracking with compound potency. The project remains open for others to carry on, however.
For answers to all the questions you have, go to the FAQs.
If you'd like to contact someone to talk about contributing, then write something in an Issue (see the tab above), which is a good way to communicate openly. (Issues describe what currently needs doing and act as a discussion forum - you need a Github account but it's super easy and not spammy. There's also an email address (chemistry@thesgc.org) you can use to ask questions. You can read more about all this in the "How To" Area
Some humans involved in this CNP:
Professor Matthew Todd, University College London. Head of Chemistry Networks at the SGC (medchem) @mattodd
Dr Álvaro Magalhães, University College London (synthetic chemistry) @alvaro-magalhaes
Dr Anwar Hossain, University of North Carolina @ahsgc
Pharma Champion: Vacant.
The Sir James Murray Student Champion: vacant
Other Contributors To Date:
Potential Contributors
You can see other contributors in the Issues (tab above).
The licence for the content of this project is, unless otherwise stated, and as for all OCN projects, CC-BY-4.0. This means you can do whatever you like with the project content, including making money, provided you cite the project.
This project is part of the SGC's Open Chemistry Networks initiative.
