The Structural Genomics Consortium

A public-private partnership supporting the discovery of medicines through open science.

Pinned Repositories

About_Open_Chem_Networks
About the SGC's Open Chemistry Networks Initiative, and News
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AIRCHECK-documentation
Internal documentation for the AIRCHECK DEL project
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CNP1-PKIS-5
1 2 30
CNP14-WDR91
4 2 90
CNP18-DENVRdrp-VirtualScreen
An SGC Chemical Networks Project devoted to the DENV Rdrp, focusing specifically on the results from a virtual screening campaign of the Enamine REAL space to identify hits. Use the link below to learn about other READDI-AViDD projects.
1 1 60
CNP25-CHIKV-nsP3-Macrodomain
This project aims to develop a chemical probe of CHIKV-nsP3-macrodomain starting from a fragment screen
1 2 60
CNP4-Nsp13-C-terminus-B
An SGC Open Chemical Networks Project Devoted to a site on the SARS-CoV-2 protein nsp13
8 4 480
CNP5-PLCZ1
An SGC Chemical Networks Project Devoted to the Target Phospholipase C Zeta 1
00
CNP6-ABHD2
An SGC Open Chemistry Networks Project Devoted to the Target α,β-Hydrolase Domain-containing Protein 2
30
Pipeline
https://docs.google.com/spreadsheets/d/1TanvenS56FovmyT8BoxloH2iHP4jjVcusho2F5nwDeU/edit?usp=sharing
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The Structural Genomics Consortium's Repositories

StructuralGenomicsConsortium/CNP18-DENVRdrp-VirtualScreen
An SGC Chemical Networks Project devoted to the DENV Rdrp, focusing specifically on the results from a virtual screening campaign of the Enamine REAL space to identify hits. Use the link below to learn about other READDI-AViDD projects.
1 1 60
StructuralGenomicsConsortium/CNP24-NSP10_14-Frags
This project aims to develop potent inhibitors of NSP14/NSP10 for the treatment of (CoV-19), Targeting the NSP14 and NSP10 interacting interface with small molecules or peptides could be a smart strategy to obstruct replication processes of coronaviruses (CoVs).
10
StructuralGenomicsConsortium/CNP25-CHIKV-nsP3-Macrodomain
This project aims to develop a chemical probe of CHIKV-nsP3-macrodomain starting from a fragment screen
1 2 60
StructuralGenomicsConsortium/Pipeline
https://docs.google.com/spreadsheets/d/1TanvenS56FovmyT8BoxloH2iHP4jjVcusho2F5nwDeU/edit?usp=sharing
10
StructuralGenomicsConsortium/CNP10-CHIKV-Naphthoquinone
An Open Chemistry Network dedicated to finding hits vs CHIKV based on a hit containing an naphthoquinone.
0 1 20
StructuralGenomicsConsortium/CNP12-Nsp15-TAMU
hello
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StructuralGenomicsConsortium/CNP15-Solubility-Analysis
00
StructuralGenomicsConsortium/CNP16-iminoquinone-SarsRdRp-mechanstic-study
00
StructuralGenomicsConsortium/CNP17-DENVRdrp-EnamineCovalent
An SGC Chemical Networks Project devoted to the DENV Rdrp, focusing specifically on exploring the Enamine covalent library. Use the link below to learn about other READDI-AViDD projects.
0 1 20
StructuralGenomicsConsortium/CNP19-CHIKVhelicase-Covalent
An SGC Open Chemistry Networks Project (number 19) dedicated to finding hits vs CHIKV nsp2 helicase based on a HTS of a Enamine Covalent library.
0 1 10
StructuralGenomicsConsortium/CNP20-CHIKVhelicase-VirtualScreen
An SGC Open Chemistry Networks Project (number 20) dedicated to finding hits vs CHIKV nsp2 helicase based on a Virtual Screen of Enamine REAL compounds.
0 1 00
StructuralGenomicsConsortium/CNP21-CHIKVhelicase-Asinex
An SGC Open Chemistry Networks Project (number 21) dedicated to finding hits vs CHIKV nsp2 helicase based on a HTS of a Asinex library.
0 1 30
StructuralGenomicsConsortium/CNP8-Nsp13-Indoles
An Open Chemistry Network dedicated to finding hits vs SARS-CoV-2 Nsp13 based on a hit containing an indole.
0 2 20
StructuralGenomicsConsortium/CNP11-DENVRdrp-LifeChem
An SGC Chemical Networks Project devoted to the DENV Rdrp, focusing specifically on exploring the LifeChemicals library. Use the link below to learn about our other READDI-AViDD projects.
1 0
StructuralGenomicsConsortium/CNP22-CHIKV-Nsp2-Protease
This project aims to develop new CHICKV NSP2 protease inhibitors with high potency and selectivity as well as with an improved physicochemical properties.
1 0
StructuralGenomicsConsortium/CNP23-SARS-CoV2-RdRp
StructuralGenomicsConsortium/CNP26_DENVRdrp_ReferenceCmpds
An SGC Chemical Networks Project devoted to the DENV Rdrp, focusing specifically on identifying a DENV reference compound. If you would like to learn about other repositories in the READDI-AViDD pipeline, please use the link below.
1 0
StructuralGenomicsConsortium/CNP27-SARS-CoV-2-NSP14
This project aims to develop a chemical probe of SARS-CoV2-NSP14 starting from a fragment screen
StructuralGenomicsConsortium/CNP29_CHIKVnsp2_DEL-ML
An SGC Open Chemistry Networks Project (number 29) dedicated to finding hits vs CHIKV nsp2 helicase based on a DEL screen and subsequent machine learning by X-Chem.
StructuralGenomicsConsortium/CNP32_SARS-CoV-2_nsP13-Helicase_thiazoles
SARS-CoV-2 NSP13 helicase inhibitors development campaign based on pritelivir
StructuralGenomicsConsortium/CNP33_SARS-CoV-2_nsP12-RdRp_HTS
SARS-CoV-2 nsP12 RdRp inhibitor development campaign by HTS
StructuralGenomicsConsortium/CNP34_SARS-CoV-2_nsP13-Helicase_cheminformatics
SARS-CoV-2 nsP13 helicase inhibitors identification through data mining
StructuralGenomicsConsortium/CNP35-CHIKV-nsp2-helicase-spiro
StructuralGenomicsConsortium/CNP36-EBOV-RdRp-inhibitors
StructuralGenomicsConsortium/CNP37-CHIKV-Protease-HTS-non-covalent
StructuralGenomicsConsortium/CNP38_VEEV-nsP2-Protease_Covalent
StructuralGenomicsConsortium/CNP39-SARS2-RdRp-HTS-TAMU
StructuralGenomicsConsortium/CNP40-SARS2-RdRp-HTS-UNC
StructuralGenomicsConsortium/CNP7-RdRp-S1-Tetrazole
An Open Chemistry Networks Project Targeting SARS-CoV-2 RdRp
StructuralGenomicsConsortium/CNP9-DENVRdrp-ChEMBL
An SGC Chemical Networks Project devoted to the DENV Rdrp, focusing specifically on exploring the ChEMBL database. Please use the link below to view all projects in the READDI-AViDD pipeline.
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