eQTL mapping using RNA-seq data from tumor samples, combining Total Read Count (TReC) and allele-specific expression (ASE) of each gene, and adjust for tumor purity across samples to estimate eQTL effects for tumor and normal cells separately.
Reference: Wilson DR, Ibrahim JG, Sun W. Mapping Tumor-Specific Expression QTLs In Impure Tumor Samples. Journal of the American Statistical Association. 2019 Apr 23(just-accepted):1-24.