Two-locus selection using moments
This repository contains scripts to run the analyses and compile the manuscript for "Local fitness and epistatic effects lead to distinct patterns of linkage disequilibrium in protein-coding genes" (formerly "Can we distinguish modes of selective interactions using linkage disequilibrium?"). The manuscript is built using bookdown, and the repository was first cloned from kevin thornton's very handy rmarkdown manuscript template.
Tagged commits correspond to submissions, revisions, etc, with a short description of changes between versions.
0.1
- Initial bioRxiv submission, March 25, 2021 (doi: 10.1101/2021.03.25.437004)
0.2
- Resubmission with major revisions, April 1, 2022
Manuscript compilation uses bookdown and rmarkdown. At the very least, you need:
bookdown
rmarkdown
knitr
For analyses:
moments
>= 1.1.0 (includesscipy
andnumpy
)
For plotting:
matplotlib
bokeh