Detect Runs of Homozygosity and Runs of Heterozygosity in diploid genomes
This repository contains the source code for the R package detectRUNS and related
performance tests. Here's the directory content:
├── detectRUNS
├── performance
├── README.md
└── TODO
detectRUNS implements two statistical approaches to runs' detection:
- a sequential approach (consecutive runs, as described in Marras et al. 2015, and implemented in the software package Zanardi: https://github.com/bioinformatics-ptp/Zanardi);
- an approach based on overlapping sliding windows (à la Plink: Purcell et al. 2007)
More info in the Google Doc (https://goo.gl/yXR7iA)