simATAC is a framework provided as an R package that generates a single-cell Assay for Transposase-Accessible Chromatin sequencing (scATAC-seq) count matrix, highly resembling real scATAC-seq datasets in library size, sparsity, and averaged chromatin accessibility signals. simATAC deploys statistical functions derived from analyzing 90 real scATAC-seq cell groups to model read distributions. simATAC provides a robust and systematic approach to generate in silico scATAC-seq samples with cell labels for a comprehensive tool assessment.
Install simATAC R package (R >= 3.5.0):
$ R
> library(devtools)
> install_github("bowang-lab/simATAC")simATAC tutorial provides examples and explanations of its functions and how to use them. This documentation introduces the main features of simATAC.
Report bugs and provide suggestions by sending email to:
Author and maintainer: Zeinab Navidi (zeinab.nvd@gmail.com)
Or open a new issue on this Github page.