/scVI

Deep generative modeling for single-cell transcriptomics

Primary LanguageJupyter NotebookMIT LicenseMIT

scVI

https://travis-ci.org/YosefLab/scVI.svg?branch=master Documentation Status

Single-cell Variational Inference

Quick Start

  1. Install Python 3.6 or later. We typically use the Miniconda Python distribution.
  1. Install PyTorch. If you have an Nvidia GPU, be sure to install a version of PyTorch that supports it -- scVI runs much faster with a discrete GPU.
  1. Install scVI through conda (conda install scvi -c bioconda) or through pip (pip install scvi). Alternatively, you may download or clone this repository and run python setup.py install.
  2. Follow along with our Jupyter notebooks to quickly get familiar with scVI!
    1. data loading
    2. basic usage
    3. reproducing results from the paper

References

Romain Lopez, Jeffrey Regier, Michael Cole, Michael I. Jordan, Nir Yosef. "Deep generative modeling for single-cell transcriptomics" Nature Methods, in press (accepted Oct 26, 2018). Preprint available at https://www.biorxiv.org/content/early/2018/03/30/292037