Scimm is an unsupervised method to cluster sequences using interpolated Markov models. Scimm is initialized by clustering with LikelyBin and my version of CompostBin. PhyScimm is a partially supervised method that uses Phymm to initialize Scimm. Reference: Kelley, DR and Salzberg, SL. Clustering metagenomic sequences with interpolated Markov models. BMC Bioinformatics 11:154 2010. Website (w/ manual): http://www.cbcb.umd.edu/software/scimm