/mageck2

A next generation of CRISPR screening analysis tool

Primary LanguagePythonBSD 3-Clause "New" or "Revised" LicenseBSD-3-Clause

MAGeCK2: Model-based Analysis of CRISPR screens

MAGeCK2 is a new computational tool, built upon MAGeCK, for CRISPR screening analysis.

Compared with MAGeCK, MAGeCK2 highlights the following additional functionalities:

  • Paired sample analysis
  • Processing and analyzing screens with UMIs
  • Processing and analyzing paired-guide screens

More functions to be added.

Documentation

For instructions on installation, usage and running examples, see mageck2-doc.

Demo

You can run the example datasets of MAGeCK2 from GitHub mageck2-demo repository.

MAGeCK

The older version of MAGeCK can be accessed via sourceforge or bitbucket.

Questions

Questions? Bug? Recommendations? Here are a few ways:

Version history

2020.12.01 Version 0.1

  • Add paired-guide support in count command
  • Add UMI support in count command
  • The source code released.