minimal comentropy threshold
jimlund opened this issue · 1 comments
jimlund commented
Hi, I read the documentation about how comentropy values are used for tumor-only calling.
How does the '-i' parameter, the minimal comentropy threshold, get used? Is the default normally a reasonable value? When would it need to be changed, and what would you suggest?
Cheers,
Jim
ZhaoDanOnGitHub commented
The default value is obtained by multiple experiments on different datas for higher correct rate. Due to the different types of sequencing platforms and cancer types, it is recommended that you draw a plot of the results and choose the appropriate threshold based on the results.