Is it possible to run palantir on batch corrected data?
jesswhitts opened this issue · 2 comments
jesswhitts commented
Hello,
I was just wondering if it is possible to run this on batch corrected data? SCVI corrected to be more specific. The counts themselves are not actually altered, but "X_scVI" is used as input for dimensionality reduction rather than using PCs. So could I run this and just use "X_scVI" rather than "X_pca"?
Many thanks,
Jess
ManuSetty commented
Yes - you should be able to use X_scVI as input to computing diffusion
components
On Mon, May 22, 2023 at 03:50 jesswhitts ***@***.***> wrote:
Hello,
I was just wondering if it is possible to run this on batch corrected
data? SCVI corrected to be more specific. The counts themselves are not
actually altered, but "X_scVI" is used as input for dimensionality
reduction rather than using PCs. So could I run this and just use "X_scVI"
rather than "X_pca"?
Many thanks,
Jess
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Manu
jesswhitts commented
It works. Thanks! :)