/flux-enzyme-cost-minimization

Explore optimal metabolic states by screening of metabolic flux distributions and computing their enzyme cost via kinetic models

Primary LanguagePythonGNU General Public License v2.0GPL-2.0

Software code and example models for flux-balance enzyme cost minimization (fECM)

Meike Wortel, Elad Noor, Wolfram Liebermeister (2017)

The files in this repository are supplementary material accompanying the article

Meike T. Wortel, Elad Noor, Michael Ferris, Frank J. Bruggeman, Wolfram Liebermeister (2017) Profiling metabolic flux modes by enzyme cost reveals variable trade-offs between growth and yield in Escherichia coli. doi: https://doi.org/10.1101/111161

accessible on BioRxiv at http://biorxiv.org/content/early/2017/03/13/111161

Contact: wolfram.liebermeister@gmail.com