Feedback on diphtheria/camps model
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pratikunterwegs commented
This issue logs feedback from @ffinger on the diphtheria model model_diphtheria()
based on Finger et al. 2019, and potential next steps for package development - thanks @ffinger! If there's anything I've missed or that you'd like to add just put it in the comments.
General
- The model would also be suitable for diseases targeted by routine vaccination such as measles or pertusis
- Not suitable for diseases with different transmission dynamics such as Ebola or cholera
Demographic stratification of contacts
- There is not always good evidence for whethr or how contacts vary by demographic group in a camp setting, but the option to model this would be good to have
- Dev: Add social contacts functionality to the model, with a default assumption of homogeneous social contacts across demographic groups
Vaccination
- Reactive vaccination campaigns are often conducted in response to diphtheria outbreaks
- Dev: The model should support the {epidemics} vaccination functionality via
<vaccination>
objects
- Dev: The model should support the {epidemics} vaccination functionality via
- Reactive diphtheria vaccination campaigns may be conducted periodically every ±6 months, and may comprise of 1 - 3 doses, depending on dose availability;
- Dev: Consider whether the intended use case covers a long-term simulation which would require implementing a repeated vaccination functionality (see also #227);
- Dev: Consider whether more than one vaccination compartment/stratum needs to be implemented (as in Vacamole);
- Vaccination may only prevent symptomatic disease but may not prevent transmission
- Dev: Consider whether the model needs more compartments (
$I_s, I_{as}$ for symptomatic and asymptomatic), and how these can be linked to the hospitalisation compartment;
- Dev: Consider whether the model needs more compartments (
Population movements
- Modelling movements between camps in a metapopulation model may not be necessary for a scenario model, and it may be more appropriate to implement separate models for each camp;
- Population influxes into camps (see the
population_change
functionality) may differ in their vaccine coverage profiles, but there may not be good estimates for this- Dev: It is currently sufficient to assume that all individuals in an influx enter the susceptible compartment