TIGIT dysfunction role in CD19 CAR-T therapy for NHL
- This GitHub contains the source codes analyzed the dataset (the figures and tables to reproduce) used in Jackson & Hong et. al., "Sequential single-cell transcriptional and protein marker profiling reveals TIGIT as a marker of CD19 CAR-T cell dysfunction in patients with non-Hodgkin’s lymphoma", Cancer Discov candisc.1586.2021
- Publication URL : https://doi.org/10.1158/2159-8290.CD-21-1586
- scRNA-Seq multiplexed raw FASTQs are available at https://ega-archive.org/studies/EGAS00001005356
- Refer to workflow.md that R script files used to generate the figures and tables in the paper step by step