/rnaseq_nf

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Primary LanguageNextflowMIT LicenseMIT

rnaseq_nf

This is a rnaseq data processing pipeline based on the one in
https://github.com/ewels/nf-core-rnaseq
which is really nice nf pipeline.

Some customized modification has been done to adapt the IMP/IMBA slurm HPC

Some important modification

- add the intron length parameter for star aligner and test it 
- add the single-end reads for feature counts
- add the index .bai.bai files for the aligned bams from star
- change the base.config to adapt ii2 

issue for big number of samples (e.g. 1000 cells)

- some quality control steps need to be turned off: 
  - skip_genebody_coverage --skip_dupradar --skip_edger --sampleLevel --skip_multiqc
    in which the gene_body_coverage, dupradar and edgr and sample_corrrelation are turned off
  - multiqc is also turned off, because the multiqc can not manage for big number of samples