VCF to RDF, hco in VCF

[david4096]

One of the frustrating aspects of working with VCF across genome builds is the lack of normalized ways of representing them and accessing them within VCF. How could hco be used to generate RDF from VCF with better chromosome metadata?

Could hco be used to provide more metadata to VCF headers?

Perhaps a good first tool would be to extend a variant annotator to include this in a VCF in a controlled way.