mkanai/slalom-paper

Code for Kanai, M. et al. Meta-analysis fine-mapping is often miscalibrated at single-variant resolution. (2022)

Meta-analysis fine-mapping is often miscalibrated at single-variant resolution

This repository contains code for Kanai, M. et al. (2022). The SLALOM software is available here. Meta-analysis fine-mapping simulation pipeline is available here.

Data availability

The GBMI summary statistics for the 14 endpoints are available here and are browserble at the GBMI PheWeb website.

Citation

• Kanai, M. et al. Meta-analysis fine-mapping is often miscalibrated at single-variant resolution. Cell Genomics 2, 100210 (2022)

• The GBMI flagship paper: Zhou, W. et al. Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease. Cell Genomics 2, 100192 (2022)

• The other accompanying papers are available here.

Contact

Masahiro Kanai (mkanai@broadinstitute.org)