/hic-spermatogenesis

Chromatin Compartments and Selection on X

Primary LanguageJupyter NotebookGNU General Public License v3.0GPL-3.0

Correlating Chromatin Compartments with Selection

NB! Ongoing project scheduled to finish in January 2025.

The GH page rendered from this repo can be accessed here.

In this project, we investigate how the contact maps of High-throughput Chromatin Conformation Capture (Hi-C) can be correlated across species, and how well they correlate with regions that undergo (positive) selection. We focus on the X chromosome.

First, we reproduce some maps from a published paper, then we make the same analysis on some new data, and compare the results.

Reproducing this project

This project runs in a Linux environment and may do so too on Mac. A conda environment for the project is created like this:

conda env create -f binder/environment.yml

example event parameter