Nucleic Acids Club

  • The meeting is at 15:00 on every Wednesday at POB 2.444 unless otherwise noted.
  • The talk would be either speaker's own research (any preliminary and/or technical stuff is good) or introductions of other's paper(s).
  • It is preferable that the subject of talk is related to nucleic acids although any other related topics would be also welcomed; e.g. NA-binding proteins, ions, water, experimental/simulation techniques.
  • Room reservations can be made here: https://research.utexas.edu/acesit/pob-room-reservations

Upcoming meetings

  • Thursday 3:30 PM

2018/06/28 Naoto

Frictional effects on RNA folding.

2018/05/02 Hung

Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins
Harmon et al. and Pappu (2017) eLife 10.7554/eLife.30294

2018/04/19 Atreya

On a polymer model toward understanding of FRET signals.

2018/04/12 Huong

Direct evidence for sequence-dependent attraction between double-stranded DNA controlled by methylation
Yoo, Kim, Aksimentiev, Ha, Nat Commun 10.1038/ncomms11045

2018/04/05 Naoto

Duplex and Triplex RNA/DNA
Lesnik & Freier (2002) Biochemistry 10.1021/bi00034a013
Bacolla et al. (2015) PLOS Genetics 10.1371/journal.pgen.1005696

2018/03/29 Stuart Sevier

Properties of Gene Expression and Chromatin Structure with Mechanically Regulated Transcription
10.1101/262717

2018/03/22 Hung

Introduction to OpenMM

2018/03/13 Atreya

Review: Does DNA methylation affect nucleosome dynamics?

2018/02/08 Atreya

Shape, flexibility and packing of proteins and nucleic acids in complexes
Nidhi Rawata and Parbati Biswas (2011) PCCP 10.1039/C1CP00027F

2018/01/17 Sumit

Physics behind the mechanical nucleosome positioning code
Martijn Zuiddam, Ralf Everaers, and Helmut Schiessel (2017) Phys Rev. E 10.1103/PhysRevE.96.052412

2018/01/11 Debayan 2 pm at POB 2.444

Enhanced spontaneous DNA twisting/bending fluctuations unveiled by fluorescence lifetime distributions promote mismatch recognition by the Rad4 nucleotide excision repair complex
S Chakraborty, PJ Steinbach, D Paul, H Mu, S Broyde, JH Min, A Ansari (2017) NAR 10.1093/nar/gkx1216

2017/12/20 Huong (3 pm at POB 2.404B)

Ribosomes are optimized for autocatalytic production
S Reuveni, M Ehrenberg & J Paulsson (2017) Nature 10.1038/nature22998

2017/12/13 Naoto (3 pm at POB 2.404B)

Sequence-dependent persistence length of DNA
HM Chuang et al. and KD Dorfman (2017) Phys Rev Lett 10.1103/PhysRevLett.119.227802

2017/12/06 Hung

RNA phase transitions in repeat expansion disorders
Ankur Jain & Ronald D. Vale (2017) Nature 10.1038/nature22386

2017/11/08 Upayan

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins
Y Lin, et al. and Roy Parker, Mol. Cell (2015) 10.1016/j.molcel.2015.08.018

References :

2017/11/01 Sumit

DNA spools under tension (derivation)
I. M. Kulić and H. Schiessel, PRL (2004) 10.1103/PhysRevLett.92.228101

2017/10/25 @ POB 2.444 Debayan

Crowding-Induced Hybridization of Single DNA Hairpins
L.E. Baltierra-Jasso, ..., S.W. Magennis, JACS (2015) http://dx.doi.org/10.1021/jacs.5b11829

2017/10/18 @ POB 2.444 Naoto

Toehold Switches: De-Novo-Designed Regulators of Gene Expression
A.A. Green, ..., Peng Yin, Cell (2014) http://dx.doi.org/10.1016/j.cell.2014.10.002

Complex cellular logic computation using ribocomputing devices
A.A. Green, ..., Peng Yin, Nature (2017) http://dx.doi.org/10.1038/nature23271

2017/09/20 @ POB 2.444 Hung

Estimation of Relative Protein–RNA Binding Strengths from Fluctuations in the Bound State
Zhaleh Ghaemi, ..., Martin Gruebele, and Zaida Luthey-Schulten, JCTC (2016) http://dx.doi.org/10.1021/acs.jpcb.7b04318

2017/09/11 @ POB 2.444 Atreya

Packing Defects Propagated During the Growth of Toroidal Condensates by Semiflexible Polymer Chains

2017/09/05 @ POB 2.444 Sumit

Stretching of Homopolymeric RNA Reveals Single-Stranded Helices and Base-Stacking
Seol, Skinner, Visscher, PRL (2007) https://journals.aps.org/prl/pdf/10.1103/PhysRevLett.98.158103

Relevant papers
https://journals.aps.org/prl/pdf/10.1103/PhysRevLett.84.2160
https://journals.aps.org/pre/pdf/10.1103/PhysRevE.70.020902

2017/08/28 Upayan

On the dynamic correlation of water

2017/08/21 Upayan @ POB 2.404B

On the spatial correlation of water

2017/08/14 Sumit @ POB 2.444

DNA spools under tension
I. M. Kulić and H. Schiessel, PRL (2004) 10.1103/PhysRevLett.92.228101

Why Do Nucleosomes Unwrap Asymmetrically?
Bruin et al. and Helmut Schiessel, JPCB (2016) 10.1021/acs.jpcb.6b00391

2017/08/07 Naoto @ POB 2.444

Molecular determinants of the interactions between proteins and ssDNA
Mishra and Levy, PNAS (2015) 10.1073/pnas.1416355112

2017/07/31 Hung

RNA model with explicit Mg and implicit monovalent

2017/07/26 Debayan

Hoogsteen base pairing in DNA

2017/07/03 Naoto

Visualizing the secondary and tertiary architectural domains of lncRNA RepA
Liu, Somarowthu and Pyle (2017) 10.1038/NCHEMBIO.2272

2017/06/26 Hung

Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues
Das and Pappu, PNAS (2013) 10.1073/pnas.1304749110

2017/06/19 Debayan

Opposing Effects of Multivalent Ions on the Flexibility of DNA and RNA
Drozdetski et al. and Onufriev, PRL (2016) 10.1103/PhysRevLett.117.028101

2017/06/05 Sabeeha @ 2pm, POB 2.444

Memory-induced anomalous dynamics: Emergence of diffusion, subdiffusion, and superdiffusion from a single random walk model
Kumar et al., Phys. Rev. E (2010) 10.1103/PhysRevE.82.021101

2017/05/22 Naoto @ 2pm, POB 2.444

Reconstruction of atomistic model and its application to footprinting data

2017/05/15 Hung @ Chemistry Library

Riboswitches and cotranscriptional folding.
Cf. Grilley et al., Biochem. (2007) 10.1021/bi062284r
Cf. Leipply et al., Biochem. (2011) 10.1021/bi101948k

2017/05/08 Debayan

Dynamical Disorder in the DNA hydration shell
Duboué-Dijon et al., JACS (2016) 10.1021/jacs.6b02715

2017/04/17 Sabeeha

Kinetics of polymer looping with macromolecular crowding: effects of volume fraction and crowder size
Shin et al., Soft Matter (2015) 10.1039/C4SM02007C

2017/04/03 Naoto

Stress-Triggered Phase Separation Is an Adaptive, Evolutionarily Tuned Response
Riback et al., Cell (2017) 10.1016/j.cell.2017.02.027

2017/03/27 Hung

On the treatment of electrostatic interaction in coarse-grained models

2017/03/20 Debayan

2017/03/13 Sabeeha

On the diffusion along DNA

2017/03/06 Naoto

Folding kinetics of Azoarcus ribozyme

2017/02/27 Hung

On the semi-implicit ion model

2017/02/20 Debayan

Probing helical transition in a DNA duplex
Chakraborty and Wales, PCCP (2017) 10.1039/c6cp06309h