/ils-pipeline

ABBA-BABA test conducted on Saccharomyces cerevisiae strains using whole-genome alignment.

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ils-pipeline

29/12/2023 this page is under construction.

The pipeline specificaly test for the quartet: Wine/Eurepean S.cerevisiae (P1) - S.cerevisiae test sample (P2) - European Saccharomyces paradoxus (P3) - Saccharomyces jurei (O).

A schematic about the ABBA and BABA patterns across P1, P2, P3, and O.

In contrast to other software, the 'D function' executes a formula where the numerator is determined by the difference between BABA and ABBA.

Negative, statistically significant D values, indeed support the presence of introgression.

In the case of ILS, the occurrence of both ABBA and BABA patterns is typically random and not biased in a way that would suggest introgression, thus not leading to a significant result in the ABBA-BABA test.

Therefore, a significant result in an ABBA-BABA test is more likely indicative of introgression rather than being attributable to ILS.

The interpretation of ABBA-BABA test can be challenging and require additional lines of evidence and a thorough understanding of the evolutionary history of the organism of interest.

About admixtr : https://bodkan.net/admixr/

About ILS: https://theg-cat.com/2021/03/01/incomplete-lineage-sorting-through-pachinko-a-visual-analogy/

About ABBA-BABA test: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100745/bin/NIHMS827403-supplement-Supplement.pdf (Green et al., 2010)

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