/TransTEx

R package for TransTEx: Novel tissue-specificity scoring method for grouping human transcriptome in-to different expression groups

Primary LanguageRMIT LicenseMIT

TransTEx (Transcript-level Tissue Expression)

Novel tissue-specificity scoring method for grouping human transcriptome into different expression groups

TransTEx is a comprehensive R package developed by the Davuluri Lab for analyzing and exploring tissue-specific transcript/gene expression patterns. The package facilitates the identification of tissue-specific and tissue-enhanced transcripts across various conditions, leveraging bulk-transcriptomic data to uncover insights into gene expression dynamics.

Citation

Pallavi Surana, Pratik Dutta, Ramana V Davuluri, TransTEx: novel tissue-specificity scoring method for grouping human transcriptome into different expression groups, Bioinformatics, Volume 40, Issue 8, August 2024, btae475, https://doi.org/10.1093/bioinformatics/btae475

Database

https://bmi.cewit.stonybrook.edu/transtexdb/

Installation

Before installing TransTEx, ensure you have R installed on your system. TransTEx can be installed directly from GitHub using the remotes package. If you do not have remotes installed, you can install it using the following command:

install.packages("remotes")

With remotes installed, proceed to install TransTEx:

remotes::install_github("pallavisurana1/TransTEx")

Quick Start

Load TransTEx into your R session:

library(TransTEx)

Explore the functions and datasets provided by TransTEx:

help(package = "TransTEx")

Usage Examples

For detailed examples of using TransTEx to analyze tissue-specific gene expression, please refer to the vignettes:

browseVignettes("TransTEx")

Reporting Issues

If you encounter any bugs or issues while using TransTEx, please report them on the Issues page of the GitHub repository. We appreciate your contributions to improving TransTEx.

Contact

For additional information or inquiries about TransTEx, please contact Pallavi Surana (pallavi.surana@stonybrook.edu)

License

TransTEx is made available under the (specify license, e.g., MIT License). See the LICENSE file for more details.