/edgePy

A Python implementation of edgeR for differential expression analysis.

Primary LanguagePythonGNU General Public License v3.0GPL-3.0

edgePy

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The edgePy library will become an implementation of edgeR for differential expression analysis in the Python language. This library will have advantages over edgeR in that it will be well-tested and will run faster by utilizing Cythonized routines. edgePy will maintain the functionality of edgeR in that it's primary goals are differential expression analysis of RNA-Seq expression profiles with biological replication. The statistical methods for negative binomial distributions will include empirical Bayes estimations, exact tests, generalized linear models, and quasi-likelihood tests.

Project Aims

The edgePy library will be used for data import, normalization with respect to conditions, application of generalized linear models, and visualization.