Make module for seashore-ludlow analysis

[ScottCampit]

Steps for drug sensitivity analysis:

• Make code from Shen et al into a MATLAB function
• Put AUC data in right format in MATLAB variable
• Ensure that H3 relative values are formatted correctly
• Run with bulk methylation genome scale metabolic model unconstrained (without inhibitor gene expression)
• Analyze the results

Validation steps:

• Use Le Roy et al data for proteomics instead of H3 relative values from the CCLE database
  • Create a MATLAB variable containing the methylation data

Next steps:

• Add individual methylation reactions for specific metabolic markers onto the genome-scale model and save as a new metabolic model
• Run same analysis to see if we can predict drug sensitivity for specific histone markers rather than bulk methylation.